Susan K Gilmour Selected Research

Eflornithine (Ornidyl)

1/2022	Difluoromethylornithine (DFMO) Enhances the Cytotoxicity of PARP Inhibition in Ovarian Cancer Cells.
9/2016	Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression.
7/2015	Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma.
3/2014	Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment.
9/2011	A prolonged and exaggerated wound response with elevated ODC activity mimics early tumor development.
12/2008	ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma.
1/2002	Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase and deacetylase activities in murine skin and tumors.

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Susan K Gilmour Research Topics

Disease

26	Neoplasms (Cancer) 01/2022 - 01/2002
10	Carcinogenesis 02/2019 - 01/2005
3	Melanoma (Melanoma, Malignant) 01/2021 - 07/2013
3	Inflammation (Inflammations) 02/2019 - 09/2011
3	Neoplasm Metastasis (Metastasis) 12/2016 - 11/2010
3	Neuroblastoma 09/2016 - 12/2008
2	Ovarian Neoplasms (Ovarian Cancer) 01/2022 - 12/2016
2	Skin Neoplasms (Skin Cancer) 01/2019 - 11/2007
2	Breast Neoplasms (Breast Cancer) 07/2013 - 11/2010
1	Non-alcoholic Fatty Liver Disease 02/2019
1	Fatty Liver 02/2019
1	Obesity 02/2019
1	Hypertriglyceridemia 02/2019
1	Starvation 10/2017
1	Ascites 12/2016
1	Encephalitis (Encephalitis, Rasmussen) 07/2015
1	African Trypanosomiasis (Nagana) 07/2015
1	Wounds and Injuries (Trauma) 09/2011
1	Hyperplasia 09/2011
1	Contact Dermatitis (Eczema, Contact) 01/2011
1	Neoplasm Micrometastasis 11/2010
1	Weight Loss (Weight Reduction) 11/2010
1	Ataxia Telangiectasia (Louis Bar Syndrome) 04/2008

Drug/Important Bio-Agent (IBA)

21	PolyaminesIBA 01/2022 - 01/2002
9	Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA 03/2014 - 01/2005
7	Eflornithine (Ornidyl)FDA Link 01/2022 - 01/2002
7	EnzymesIBA 09/2016 - 01/2002
4	Thrombin FDA Link 01/2022 - 11/2010
4	Proteins (Proteins, Gene)FDA Link 01/2018 - 08/2006
3	Proteinase-Activated ReceptorsIBA 01/2022 - 11/2010
3	FibrinIBA 01/2022 - 11/2010
3	Dabigatran FDA Link 12/2016 - 11/2010
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 12/2016
2	CytokinesIBA 01/2022 - 12/2016
2	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 11/2010
2	PLX 4720IBA 01/2021 - 01/2018
2	LigandsIBA 01/2021 - 07/2013
2	matrigelIBA 01/2021 - 11/2010
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 12/2016
2	Thromboplastin (Tissue Factor)IBA 12/2016 - 01/2015
2	AntithrombinsIBA 12/2016 - 11/2010
2	Pharmaceutical PreparationsIBA 07/2015 - 07/2013
2	CarcinogensIBA 09/2011 - 11/2010
2	Protein Isoforms (Isoforms)IBA 08/2007 - 08/2006
2	Transcription Factors (Transcription Factor)IBA 08/2007 - 08/2006
2	Histone Acetyltransferases (Histone Acetyltransferase)IBA 08/2006 - 01/2002
2	ChromatinIBA 11/2003 - 01/2002
2	Histones (Histone)IBA 11/2003 - 01/2002
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022
1	rucaparibIBA 01/2022
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2022
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022
1	Chemotactic FactorsIBA 01/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021
1	Immune Checkpoint InhibitorsIBA 10/2020
1	Meglumine FDA Link 02/2019
1	HMGB1 Protein (HMG1)IBA 01/2019
1	Toll-Like Receptor 4IBA 01/2019
1	ArsenicIBA 01/2019
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2018
1	Granzymes (Granzyme)IBA 10/2017
1	Peptides (Polypeptides)IBA 10/2017
1	AntigensIBA 10/2017
1	Interleukin-10 (Interleukin 10)IBA 12/2016
1	Cisplatin (Platino)FDA LinkGeneric 12/2016
1	Celecoxib (Celebrex)FDA Link 09/2016
1	CationsIBA 09/2016
1	Complement System Proteins (Complement)IBA 07/2015
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2015
1	ArginaseIBA 01/2015
1	Oxidoreductases (Dehydrogenase)IBA 03/2014
1	anthraceneIBA 03/2014
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2014
1	afimoxifene (hydroxytamoxifen)IBA 03/2014
1	DiaminesIBA 07/2013
1	naphthaleneIBA 07/2013
1	butaneIBA 07/2013
1	Dexamethasone (Maxidex)FDA LinkGeneric 09/2011
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 09/2011
1	Extracellular Matrix ProteinsIBA 11/2007
1	PutrescineIBA 11/2007
1	CREB-Binding ProteinIBA 08/2007
1	Messenger RNA (mRNA)IBA 08/2006
1	TeaIBA 01/2005
1	Drinking WaterIBA 01/2005
1	PolyphenolsIBA 01/2005
1	Nucleosomes (Nucleosome)IBA 11/2003
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2002

Therapy/Procedure

7	Therapeutics 01/2021 - 11/2010
2	Immunotherapy 10/2020 - 07/2015
2	Drug Therapy (Chemotherapy) 09/2016 - 07/2015
2	Oral Administration 01/2015 - 11/2010
1	Radiotherapy 07/2015
1	Neoadjuvant Therapy 03/2014
1	Chemoprevention 11/2007